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Title   근치적 절제술을 시행받은 위암환자에서 수술전 혈청 CEA 치의 측정 ( Determination of Preoperative Serum CEA Level in Curativeal Resected Gastric Cancer )
Publicationinfo   1996 Jan; 028(06): 1050-1055.
Key_word   Gastric cancer, Curative resection, CEA, Prognostic factor, Detection of recurrence
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Abstract   Background: Although the role of serum carcinoembryonic antigen(CEA) as a tumor marker in gastric cancer remains unanswered, several reports suggested the usefulness of serum CEA as prognostic factor or indicator of recurrence. Methods: Preoperative serum levels of CEA were determined in 79 patients with curatively resected gastric cancer and its correlation with clinicopathologic characteristics was investigated. Results: Serum CEA was positive(defined as>5ng/ml) in 16 patients(20.3%). The mean age of CEA positive group(62.9¡¾7.5 years) was significantly older than that of the negative group(53.2¡¾12.7 years)(p=0.005), and Borrmann type III cases were more frequent in CEA positive group(56.3% vs. 19.0%)(p=0.026). There were no significant differences between two groups in other clinicopathologic characteristics, including tumor size, tumor location, differentiation of tumor, and stages. Conclusion: Serum CEA does not seem to be standard. tumor marker of gastric cancer, in terms of screening or diagnosis. However, it could be useful as prognostic factor or for early detection of recurrence in curatively resected gaxtric cancer
저 자   최진혁(Jin Hyuk Choi),이선영(Sun Young Lee),심강섭(Kang Sup Shim),손혜영(Hye Young Son),이기현(Ki Youl Seo),김종선(Jong Seon Kim),박진아(Jin Ah Park),홍은순(Eun Soon Hong),김효정(Hyo Jeong Kim),박수영(Su Young Park),황민규(Min Gyeu Hwang),심광섭(Kang Sup Shim)